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Muscle Hypertrophy, Dysphagia, and Gait Abnormalities (French Bulldog Type) – Fast & Reliable Standalone Test

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Test Overview:

French Bulldogs are prone to several musculoskeletal and neurological conditions that can impact their mobility and overall health. Muscle Hypertrophy: This condition involves excessive muscle growth, often seen in the head, shoulders, and limbs, giving the dog a bulky appearance. It can be linked to genetic factors, overactive muscle development, or neuromuscular disorders. In some cases, hypertrophic muscle changes may contribute to stiffness or difficulty in movement. Dysphagia: Difficulty swallowing (dysphagia) in French Bulldogs can result from congenital abnormalities, such as brachycephalic airway syndrome, or neuromuscular disorders affecting the esophagus. Affected dogs may struggle with eating, show signs of regurgitation, or be at risk of aspiration pneumonia. Gait Abnormalities: These can range from subtle uncoordinated movements to pronounced lameness. French Bulldogs may develop gait issues due to conditions like intervertebral disc disease (IVDD), hip dysplasia, or spinal malformations (such as hemivertebrae). Neuromuscular diseases can also contribute to unsteady movement or weakness in the limbs.

Category:

Musculoskeletal - Associated with muscles, bones and associated structures

Gene:

CLCN1 gene

Variant Detected:

8 bp insertion in exon 21

Severity:

Moderate. This disease can cause significant signs of discomfort and/or dysfunction in affected animals. It may involve relatively high treatment/management costs, and can sometimes reduce life expectancy.

Mode of Inheritance:

Autosomal Recessive

Research Citation(s):

Shelton et al. Animals (Basel). 2024 Feb 25;14(5):722. doi: 10.3390/ani14050722

Associated Breed(s):

French Bulldog,

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