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Dilute D2 Variant (Chow Chow Type)

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Test Overview:

Avoid breeding two carriers of the D2 variant together to prevent dilute offspring with potential CDA risk. Carriers can be bred to clear dogs, but offspring should be tested before breeding. This helps maintain genetic diversity while reducing risk of coat colour dilution-associated problems.

Category:

Trait (Associated with Phenotype)

Gene:

MLPH

Variant Detected:

c.705G>C

Severity:

It is a trait and so is tested based on preference, not usually for health concerns.

Mode of Inheritance:

Autosomal Recessive

Research Citation(s):

Bauer A. et al (2018): A novel MLPH variant in dogs with coat colour dilution. Anim Genet. 49(1):94-97. doi: 10.1111/age.12632. Epub 2018 Jan 19

Associated Breed(s):

Basenji, Chow Chow, French Bulldog, Labradoodle , Labradoodle Retrodoodle , Labrador Retriever, Mixed Breed, Pug, Sloughi, Staffordshire Bull Terrier , Standard Poodle,
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