/ 0

Store

Gastrointestinal Polyposis

$50

(ONLINE PRICE)

ADD TO CART

Test Overview:

Gastrointestinal Polyposis affects dogs and is a disease where benign (non-cancerous) or malignant (cancerous) polyps (growths) will form in the stomach, intestines or colon. Most polyps (growths) are asymptomatic, however larger polyps can cause chronic blood loss, digestive tract obstruction and abdominal pain.

Category:

Digestive system / Gastrointestinal - Associated with the organs and structures of the digestive system

Gene:

APC

Variant Detected:

chr3: c.[462_463delinsTT]

Severity:

Moderate-Severe. This is a disease with significant welfare impact on the affected animal, in terms of clinical signs and generally reduced life expectancy.

Mode of Inheritance:

Autosomal Dominant

Recommended Screening:

Genetic testing of the APC gene will reliably determine if a dog is a genetic carrier of Gastrointestinal Polyposis. Screening tests: Endoscopy (examination of the stomach and intestines can detect polyps), Ultrasound (can be used to visualise polyps) and Biopsy (a tissue sample from a polyp can be examined under a microscope to determine if it is malignant or benign).

Research Citation(s):

https://pubmed.ncbi.nlm.nih.gov/37505844/

Associated Breed(s):

Jack Russell Terrier,

##parent-placeholder-8bfb4e1aa590eab8f08f837b97acf5803a5737ed##