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Myotonia Congenita (American Bulldog Type)

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Test Overview:

Myotonia Congenita (American Bulldog Type) affects dogs and is an inherited musculoskeletal disorder. Dogs affected with this disorder can present with a stiff-legged gait as early as 8 weeks of age. Increased respiratory sounds may also occur when the dog becomes excited. Dogs may also have difficulties swallowing food and water. In later stages of the disorder, affected dogs may collapse with a rigid body and extended limbs. Affected dogs can recover from the collapse quickly and may show gait improvements with prolonged activity. These signs are caused by abnormal electrolyte channels in the muscles. Dogs with a mild presentation may live a normal life, while more severe presentation may require medical treatment with varied success.

Category:

Musculoskeletal - Associated with muscles, bones and associated structures

Gene:

CLCN1

Severity:

Moderate. This disease can cause significant signs of discomfort and/or dysfunction in affected animals. It may involve relatively high treatment/management costs, and can sometimes reduce life expectancy.

Mode of Inheritance:

Autosomal Recessive

Recommended Screening:

Genetic testing of the CLCN1 gene will reliably determine if a dog is a genetic carrier of Myotonia Congenita.

Associated Breed(s):

American Bulldog ,

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