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Spongy Degeneration with Cerebellar Ataxia (SDCA2) Belgian Shepherd

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Test Overview:

Spongy Degeneration with Cerebellar Ataxia is a severe neurodegenerative disease that is inherited in Belgian Shepherd dogs. Symptoms for this disease will usually appear within 4 weeks and worsen. Symptoms include seizures and loss of coordination. Generally, dogs will die or be euthanised at around 8-12 weeks.

Category:

Nervous system / Neurologic - Associated with the brain, spinal cord and nerves

Gene:

SDCA2

Variant Detected:

c.130_131ins227

Severity:

Severe. This disease has a high impact on affected animals, either with severe clinical signs causing significant suffering, or carrying a rapidly fatal course.

Mode of Inheritance:

Autosomal Recessive

Recommended Screening:

Genetic testing of the SDCA2 gene will reliably determine if a dog is a genetic carrier of Spongy Degeneration with Cerebellar Ataxia (SDCA2) Belgian Shepherd.

Research Citation(s):

Mauri, 2017, G3, 7(8);2730-2737

Associated Breed(s):

Belgian Groenendael Shepherd, Belgian Lakenois Shepherd, Belgian Malinois Shepherd, Belgian Tervueren Shepherd ,

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