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Progressive Retinal Atrophy RCD2 (Collie Type)

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Test Overview:

Progressive Retinal Atrophy RCD2 specifically affects Collies and is a disease that causes blindness. Affected dogs will present with the abnormal development of the photoreceptors (rods and cones). The development of these photoreceptors will eventually degenerate. Although both photoreceptors will degenerate, the rods will degenerate at a faster rate, therefore the night blindness occurs first.

Category:

Ophthalmologic - Associated with the eyes and associated structures

Gene:

RD3

Severity:

Moderate. This disease can cause significant signs of discomfort and/or dysfunction in affected animals. It may involve relatively high treatment/management costs, and can sometimes reduce life expectancy.

Mode of Inheritance:

Autosomal Recessive

Recommended Screening:

Electroretinography (ERG) can detect retinal dysfunction in affected dogs.

Research Citation(s):

Thierry Vilboux, Gilles Chaudie et. al.: Progressive Retinal Atrophy in Border Collie: A new XLPRA (BMC Vet Res. 2008 Mar 3;4:10)

Associated Breed(s):

Collie Rough, Collie Smooth,

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