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Delayed Postoperative Haemorrhage (Scottish Deerhound Type)

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Test Overview:

Delayed Postoperative Haemorrhage is a possible fatal disorder whereby premature dissolution of blood clots during haemocoagulation is prevented. The disease causes excessive bleeding after trauma or surgery. Generally dogs will not exhibit any clinical signs or symptoms and will lead healthy lives. The dangerous issue only arises in the case of severe trauma or surgery.

Category:

Haemolymphatic - Associated with the blood and lymph

Gene:

SERPINF2

Variant Detected:

c.605C>T

Severity:

Moderate. This disease can cause significant signs of discomfort and/or dysfunction in affected animals. It may involve relatively high treatment/management costs, and can sometimes reduce life expectancy.

Mode of Inheritance:

Autosomal Recessive

Recommended Screening:

Genetic testing can determine if a dog is a carrier of Delayed Postoperative Haemorrhage disease.

Research Citation(s):

Court, M.H., Kiser, J.N., Neibergs, H.L., Zhu, Z., Dillberger, J.E. : Identification by whole genome sequencing of genes associated with delayed postoperative hemorrhage in Scottish deerhounds. J Vet Intern Med 37:510-517, 2023. Pubmed reference: 36780177

Associated Breed(s):

Scottish Deerhound,

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