Progressive Retinal Atrophy - Swedish Vallhund Type

Category:

Ophthalmologic - Associated with the eyes and associated structures

Gene:

MERTK

Variant Detected:

Insertion Ch 17

Severity:

Moderate-Severe. This is a disease with significant welfare impact on the affected animal, in terms of clinical signs and generally reduced life expectancy.

Mode of Inheritance:

Autosomal Recessive

Research Citation(s):

Everson, R., Pettitt, L., Forman, O. P., Dower-Tylee, O., McLaughlin, B., Ahonen, S., … Ricketts, S. L. (2017). An intronic LINE-1 insertion in MERTK is strongly associated with retinopathy in Swedish Vallhund dogs. PLoS ONE, 12(8), 1–14. View the article

Associated Breed(s):

Swedish Vallhund, Unknown,