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Hereditary Vitamin D-Resistant Rickets Type II

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Category:

Metabolic - Associated with the enzymes and metabolic processes of cells

Gene:

VDR

Variant Detected:

deletion

Severity:

Moderate-Severe. This is a disease with significant welfare impact on the affected animal, in terms of clinical signs and generally reduced life expectancy.

Mode of Inheritance:

Autosomal Recessive

Research Citation(s):

LeVine, D. N., Zhou, Y., Ghiloni, R. J., Fields, E. L., Birkenheuer, A. J., Gookin, J. L., Roberston, I. D., Malloy, P. J., & Feldman, D. (2009). Hereditary 1,25-dihydroxyvitamin D-resistant rickets in a pomeranian dog caused by a novel mutation in the vitamin D receptor gene. Journal of Veterinary Internal Medicine

Associated Breed(s):

Pomeranian, Unknown,

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