Haemophilia A - Havanese Type

Category:

Haemolymphatic - Associated with the blood and lymph

Gene:

FVIII

Variant Detected:

Insertion on X chromosome

Severity:

Moderate. This disease can cause significant signs of discomfort and/or dysfunction in affected animals. It may involve relatively high treatment/management costs, and can sometimes reduce life expectancy.

Mode of Inheritance:

Autosomal X-Linked

Research Citation(s):

Wilhelm C, Czwalinna A, Hoffmann M, Mischke R, Ganser A, Von Depka M. A mutation leading to a stop codon in the FVIII gene is the cause of severe canine Hemophilia A. J Thromb Haemost 1 Sup P0672, 2013.

Associated Breed(s):

Havanese, Unknown,