/ 0

Store

Canine Multiple System Degeneration (Chinese Crested)

$50

(ONLINE PRICE)

ADD TO CART

Test Overview:

Do not breed affected dogs (homozygous for the mutation). Avoid carrier × carrier matings to prevent 25% risk of producing affected puppies. Breed carriers only to genetically clear dogs to maintain genetic diversity while decreasing disease incidence. Routine genetic screening of breeding stock is strongly advised.

Category:

Nervous system / Neurologic - Associated with the brain, spinal cord and nerves

Gene:

SERAC1

Variant Detected:

c.128+1_128+4delGTAA

Severity:

Low-Moderate. This disease can cause some discomfort and/or dysfunction in the affected animal. It does not generally affect life expectancy.

Mode of Inheritance:

Autosomal Recessive

Research Citation(s):

Johnson GS, Mhlanga-Mutangadura T, Morava E, Kozicz T, Taylor JF, O’Brien DP, Schnabel RD. Canine Multiple System Degeneration is Associated with Distinct SERAC1 Mutations in Two Different Dog Breeds [abstract]. Presented at the 63rd Annual Meeting of the American Society of Human Genetics in Boston, Massachusetts; 2013 Oct 22-26.

Associated Breed(s):

Chinese Crested, Mixed Breed,

##parent-placeholder-19bd1503d9bad449304cc6b4e977b74bac6cc771##