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ARSACS (Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay) (Great Pyrenees Type)

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Test Overview:

Do not breed affected dogs (homozygous for the SACS deletion) to avoid producing affected puppies. Avoid carrier × carrier matings, which have a 25% risk of producing affected offspring per litter. Breed carriers only to clear (non-carrier) dogs to prevent affected puppies, though some offspring may be carriers. Routine genetic screening is recommended for all breeding Great Pyrenees dogs to identify carrier status and guide responsible breeding. Breed clubs and veterinary genetics organisations may provide specific recommendations to reduce disease prevalence while maintaining genetic diversity.

Category:

Haemolymphatic - Associated with the blood and lymph

Gene:

SACS

Severity:

It is a trait and so is tested based on preference, not usually for health concerns.

Mode of Inheritance:

Dominant with Variable Expressivity

Associated Breed(s):

Great Pyrenees,

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