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Factor XII Deficiency, Variant 3 (Feline)

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Test Overview:

Genetic testing can identify carriers and affected individuals. Avoid breeding two carriers of the Variant 3 mutation to prevent affected offspring. Mating carriers with clear cats produces carriers or clear kittens but no affected kittens. As the condition is asymptomatic, breeding decisions may be balanced with consideration for overall genetic diversity.

Category:

Haemolymphatic - Associated with the blood and lymph

Gene:

F12

Variant Detected:

c.1631G>C

Severity:

Low. This disease generally causes mild signs of disease, or can be quite easily treated/managed.

Mode of Inheritance:

Autosomal Recessive

Associated Breed(s):

Mixed Breed / Unknown Breed (Feline),
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