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Cystinuria, Type B, Variant 1 (Feline)

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Test Overview:

Because cystinuria Type B Variant 1 is autosomal recessive, cats must inherit two copies of the mutated gene to be affected. Breeding recommendations include: Test breeding cats to identify carriers and affected individuals. Avoid breeding two carriers together since there is a 25% chance to produce affected offspring. Mating a carrier to a clear (non-carrier) cat produces unaffected kittens; roughly 50% carriers and 50% clear. Gradually reduce the mutation frequency over generations while maintaining genetic diversity.

Category:

Urinary system / Urologic - Associated with the kidneys, bladder, ureters and urethra

Gene:

SLC7A9

Severity:

Low-Moderate. This disease can cause some discomfort and/or dysfunction in the affected animal. It does not generally affect life expectancy.

Mode of Inheritance:

Autosomal Recessive

Associated Breed(s):

Mixed Breed / Unknown Breed (Feline),
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