/ 0
Store

Find Products

Curly Coat - Cornish Rex

$50

(ONLINE PRICE)

ADD TO CART

Test Overview:

This genetic trait test identifies the causative mutation for Curly/ Wooly hair in the Cornish Rex. The cu mutation that is found on the LPAR6 gene is involved in hair and coat phenotypes in mammals. There are two copies of the cu mutation that are fixed in most Cornish Rex cats and as a result, produce a curly coat. Cats that are homozygous cu/cu show a wavy coat with no guard hairs. Outcrossing of Cornish Rex cats show that cats who have only one copy of cu mutation and one copy of wildtype Cu gene don't have curly coats, but rather exhibit typical straight coats.

Category:

Trait (Associated with Phenotype)

Gene:

LPAR6

Variant Detected:

c.250_253_delTTTG

Severity:

It is a trait and so is tested based on preference, not usually for health concerns.

Mode of Inheritance:

Autosomal Recessive

Research Citation(s):

Zorc, M., Horvat, T., Tansek, A., Ferme, T., Dovc, P. : Selection signatures reveal candidate genes for the Cornish Rex breed-specific phenotype. Genes (Basel) 15:368, 2024. Pubmed reference: 38540427. DOI: 10.3390/genes15030368. Rodney, A.R., Buckley, R.M., Fulton, R.S., Fronick, C., Richmond, T., Helps, C.R., Pantke, P., Trent, D.J., Vernau, K.M., Munday, J.S., Lewin, A.C., Middleton, R., Lyons, L.A., Warren, W.C. : A domestic cat whole exome sequencing resource for trait discovery. Sci Rep 11:7159, 2021. Pubmed reference: 33785770. DOI: 10.1038/s41598-021-86200-7. Gandolfi, B., Alhaddad, H., Affolter, V.K., Brockman, J., Haggstrom, J., Joslin, S.E., Koehne, A.L., Mullikin, J.C., Outerbridge, C.A., Warren, W.C., Lyons, L.A. : To the root of the curl: A signature of a recent selective sweep identifies a mutation that defines the Cornish rex cat breed. PLoS One 8:e67105, 2013. Pubmed reference: 23826204. DOI: 10.1371/journal.pone.0067105.

Associated Breed(s):

Cornish Rex,
##parent-placeholder-19bd1503d9bad449304cc6b4e977b74bac6cc771##