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Agouti

$50

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Test Overview:

Inheritance: The agouti gene (ASIP) exhibits a simple autosomal recessive inheritance pattern where: A (agouti) is dominant, producing banded hairs showing the tabby pattern. a (non-agouti) is recessive, resulting in self-coloured (solid) cats when two copies are present. To produce tabby-patterned cats, ensure at least one parent carries the dominant A allele (either A/A or A/a). If mating two non-agouti cats (a/a), all offspring will be solid colored. Mating an agouti cat (A/A or A/a) with a non-agouti (a/a) can produce both agouti and non-agouti kittens depending on the carrier status of the agouti parent. Genetic testing can identify whether breeding cats carry the agouti or non-agouti alleles, allowing breeders to make informed mating decisions. Be aware that other genes also influence coat patterns, so agouti status alone does not determine final appearance. Consider maintaining genetic diversity and avoiding extremes by selecting breeding pairs thoughtfully, balancing desired coat phenotype with overall health.

Category:

Trait (Associated with Phenotype)

Gene:

ASIP

Variant Detected:

a = c.123-124delCA; g.chrA3:24917970-24917971

Severity:

It is a trait and so is tested based on preference, not usually for health concerns.

Mode of Inheritance:

Complex - Mode Unknown

Research Citation(s):

Eizirik E, Yuhki N, Johnson WE, Menotti-Raymond M, Hannah SS, O'Brien SJ. Molecular genetics and evolution of melanism in the cat family. Curr Biol. 2003 Mar 4;13(5):448-53. PubMed PMID: 12620197. PubMed: 12620197 Gershony LC, Penedo MC, Davis BW, Murphy WJ, Helps CR, Lyons LA. Who's behind that mask and cape? The Asian leopard cat's Agouti (ASIP) allele likely affects coat colour phenotype in the Bengal cat breed. Anim Genet. 2014; 45(6):893-897. PubMed PMID: 25143047 PubMed: 25143047

Associated Breed(s):

Abyssinian, African Short Hair, All Breeds (Feline), American Bobtail , American Curl, American Ringtail, American Shorthair, Angora, Asian, Australian Mist , Balinese, Bengal, Birman, Bombay, British Black Tipped, British Longhair, British Red Spot, British Shorthair, British Shorthair/Longhair, Burmese, Burmilla, Calico, California Spangled, Chantilly, Chartreux, Chausie, Chinchilla, Colourpoint Siberian Forest Cat, Cornish Rex, Devon Rex, Domestic Leopard Cat, Domestic Medium / Long Hair, Domestic Short Hair, Don Hairless, Don Sphynx, Egyptian Black, Egyptian Mau, European, Exotic , Exotic Longhair, Exotic Shorthair, Foreign White, German Rex, Havana Brown, Highland Fold, Himalayan, Japanese Bobtail, Javanese, Khao Manee, Korat, Kurilian Bobtail Short Haired, LaPerm , Maine Coon, Manx , Mixed Breed / Unknown Breed (Feline), Munchkin Short/Long Haired, Norwegian Forest Cat, Ocicat, Ojos Azules, Oriental , Oriental Long Hair, Oriental Short Hair, Persian , Persian Blue, Persian Colourpoint, Persian Smoke, Persian Tabby, Peterbald, PixieBob, Ragamuffin, Ragdoll, Rex , Russian Black, Russian Blue, Russian White, Savannah, Scottish Fold, Scottish Fold Long Haired, Scottish Fold Short Haired, Scottish Short Hair, Scottish Straight, Scottish Wildcat, Selkirk Rex, Serengeti, Seychellois Short/Long Hair, Siamese, Siberian, Siberian Forest Cat, Singapura, Snowshoe, Sokoke, Somali , Somali Long Hair, Somali Short Hair, Sphynx, Tiffany, Tonkinese, Toyger, Turkish Angora, Turkish Van, York Chocolate,
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