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Factor XII Deficiency, Variant 2 (Feline)

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Test Overview:

Since the trait is autosomal recessive, avoid breeding two carriers of this mutation to prevent producing affected offspring. Breeding carrier × clear cats poses no risk of producing affected kittens but 50% of offspring will be carriers. The condition is asymptomatic, so the mutation does not compromise cat health directly. Breeding decisions should balance between reducing this mutation and maintaining genetic diversity. Consult genetic counsellors and veterinarians for management plans.

Category:

Haemolymphatic - Associated with the blood and lymph

Gene:

F12

Variant Detected:

c.1631G>C

Severity:

Low. This disease generally causes mild signs of disease, or can be quite easily treated/managed.

Mode of Inheritance:

Autosomal Recessive

Associated Breed(s):

Mixed Breed / Unknown Breed (Feline),
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