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Acute Intermittent Porphyria (Variant 4) (Siamese Type 1)

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Test Overview:

Due to autosomal dominant inheritance, breeding cats that carry the mutation is not recommended. Each offspring of a carrier has about a 50% chance of inheriting the mutant gene and being at risk for disease. Genetic testing of breeding cats is essential to identify carriers and avoid breeding affected animals. Responsible breeding practices include exclusion of carriers to reduce disease incidence while maintaining genetic diversity.

Category:

Haemolymphatic - Associated with the blood and lymph

Gene:

HMBS

Severity:

It is a trait and so is tested based on preference, not usually for health concerns.

Mode of Inheritance:

Dominant with Variable Expressivity

Associated Breed(s):

Siamese,
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