Acute Intermittent Porphyria (Variant 2)

Category:

Metabolic - Associated with the enzymes and metabolic processes of cells

Gene:

HMBS

Severity:

Low-Moderate. This disease can cause some discomfort and/or dysfunction in the affected animal. It does not generally affect life expectancy.

Mode of Inheritance:

Autosomal Dominant

Recommended Screening:

Genetic testing is recommended for all cats who have brown coloured urine or teeth.

Research Citation(s):

Clavero, S., Ahuja, Y., Bishop, D.F., Kwait, B., Haskins, M.E., Giger, U., Desnick, R.J. : Diagnosis of feline acute intermittent porphyria presenting with erythrodontia requires molecular analyses. Vet J 198:720-2, 2013. Pubmed reference: 24239138

Associated Breed(s):

Mixed Breed / Unknown Breed (Feline),