I Pheomelanin Locus Colour Intensity*

Category:

Trait (Associated with Phenotype)

Gene:

MFSD12

Variant Detected:

c.151C>T (p.Arq51Cys)

Severity:

It is a trait and so is tested based on preference, not usually for health concerns.

Mode of Inheritance:

Autosomal Recessive

Recommended Screening:

Genetic testing of the MFSD12 gene will reliably determine if a dog is a genetic carrier for I Pheomelanin Locus Colour Intensity.

Research Citation(s):

Hédan, B., Cadieu, E., Botherel, N., Dufaure de Citres, C., Letko, A., Rimbault, M., Drögemüller, C., Jagannathan, V., Derrien, T., Schmutz, S.,Leeb T., André, C. (2019) Identification of a Missense Variant in MFSD12 Involved in Dilution of Phaeomelanin Leading to White or Cream Coat Color in Dogs. Genes, 10(5):386. doi: 10.3390/genes10050386.