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E Locus (Cattle Dog Cream Variant) e2

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Test Overview:

Test Australian Cattle Dogs for the e2 allele when managing cream or pale red coat lines. Avoid mating two e2 carriers if producing cream/pale red coats is undesirable. Use genotype information to plan mate selection for colour consistency. Balance coat colour selection with health and genetic diversity goals.

Category:

Trait (Associated with Phenotype)

Gene:

MC1R

Variant Detected:

c.430G>C

Severity:

It is a trait and so is tested based on preference, not usually for health concerns.

Mode of Inheritance:

Autosomal Recessive

Research Citation(s):

Durig N, A Letko, SH Rasouliha, R Loechel, A Kehl, MK Hytonen, H Lohi, N Mauri, J Dietrich, M Wiedmer, M Drogemuller, V Jagannathan, SM Schmutz, T Leeb. 2018. Two MC1R loss-of-function alleles in cream-coloured Australian Cattle Dogs and white Huskies. Animal Genetics 49:284-290.

Associated Breed(s):

Australian Cattle Dog, Australian Shepherd, Australian Stumpy Tail Cattle Dog, Border Collie, Collie Rough, Collie Smooth, Koolie , Mixed Breed,
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