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Brown TYRP1 [Australian Shepherd Type] = Ba

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Test Overview:

Breeders should utilize genetic testing for the TYRP1 gene including the ba allele in Australian Shepherds to inform mate selection. Avoid mating two carriers of brown alleles unless brown coat color is desired. Breed carriers (heterozygous for ba or other brown alleles) to clear (black) dogs to prevent brown puppies while maintaining genetic diversity. Genetic testing for the full range of TYRP1 alleles is important to accurately predict coat color outcomes in litters.

Category:

Trait (Associated with Phenotype)

Gene:

TYRP1

Variant Detected:

ba = T>G, Chr11:33319349 (Australian Shepherd Type)

Severity:

It is a trait and so is tested based on preference, not usually for health concerns.

Mode of Inheritance:

Autosomal Recessive

Research Citation(s):

Hrckova Turnova E, Majchrakova Z, Bielikova M, Soltys K, Turna J, Dudas A. A novel mutation in the TYRP1 gene associated with brown coat color in the Australian Shepherd Dog Breed. Anim Genet. 2017 Oct; 48(5):626. [PubMed: 28497851]

Associated Breed(s):

Australian Shepherd, Border Collie, Collie Rough, Collie Smooth, Mixed Breed,
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