Myeloperoxidase Deficiency

Category:

Haemolymphatic - Associated with the blood and lymph

Gene:

MOP

Variant Detected:

C>T

Severity:

Moderate-Severe. This is a disease with significant welfare impact on the affected animal, in terms of clinical signs and generally reduced life expectancy.

Mode of Inheritance:

Autosomal Recessive

Research Citation(s):

Gentilini, F., Zambon, E., Mancini, D., & Turba, M. E. (2016). A nonsense mutation in the myeloperoxidase gene is responsible for hereditary myeloperoxidase deficiency in an Italian hound dog. Animal Genetics, 47(5), 632–633.

Associated Breed(s):

Unknown,