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Exercise Induced Metabolic Myopathy

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Test Overview:

Test breeding dogs for the ACADVL gene mutation. Avoid carrier-to-carrier matings to prevent affected offspring. Breed carriers only with clear dogs, and screen offspring before breeding. Aim to maintain genetic diversity while reducing disease prevalence.

Category:

Musculoskeletal - Associated with muscles, bones and associated structures

Gene:

ACADVL

Variant Detected:

nonsense mutation: c. 1728C>A.

Severity:

Moderate. This disease can cause significant signs of discomfort and/or dysfunction in affected animals. It may involve relatively high treatment/management costs, and can sometimes reduce life expectancy.

Mode of Inheritance:

Autosomal Recessive

Recommended Screening:

Genetic testing of the ACADVL gene will reliably determine if a dog is a genetic carrier of Exercise Induced Metabolic Myopathy.

Associated Breed(s):

Mixed Breed,
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