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Dental Skeletal Retinal Anomaly [Cane Corso Type]

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Test Overview:

Genetic testing is strongly advised for all potential breeding Cane Corsos to identify carriers and avoid producing affected puppies. To prevent DSRA, it is recommended to breed only dogs that are clear of the mutation or, at minimum, never mate two carriers. Carriers should ideally be removed from breeding programs or only bred to clear dogs, with careful pedigree management to maintain genetic diversity

Category:

Dental - Associated with the teeth and associated structures

Gene:

MIA3

Variant Detected:

deletion chr38

Severity:

Moderate. This disease can cause significant signs of discomfort and/or dysfunction in affected animals. It may involve relatively high treatment/management costs, and can sometimes reduce life expectancy.

Mode of Inheritance:

Autosomal Recessive

Recommended Screening:

Genetic testing of the MIA3 gene will reliably determine if a dog is a genetic carrier of Dental Skeletal Retinal Anomaly (Cane Corso Type).

Research Citation(s):

https://pubmed.ncbi.nlm.nih.gov/34680893/

Associated Breed(s):

Cane Corso, Mixed Breed,

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