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D Locus (Dilute) - d3

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Test Overview:

Dogs can be homozygous d3/d3 or compound heterozygous d1/d3 or d2/d3 to show diluted coat color. Identification of the d3 allele explains previously unexplained dilution cases in certain breeds. Additional MLPH variants likely exist, so comprehensive testing should consider all known alleles (d1, d2, d3).

Category:

Haemolymphatic - Associated with the blood and lymph

Gene:

MLPH

Variant Detected:

c.667_668insC

Severity:

It is a trait and so is tested based on preference, not usually for health concerns.

Mode of Inheritance:

Dominant with Variable Expressivity

Associated Breed(s):

Mixed Breed,
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